
Other Life #147 with Razib Khan
I just published a new episode of the podcast. Highlights below for your reading convenience. Highly recommend this one**,** some true galaxy brain content here.
Razib Khan writes the #1 Substack in the Science category. We talk about how to genotype your unborn baby, whether we can increase our intelligence and testosterone with CRISPR, whether Genghis Khan was good actually, how Razib is succeeding on Substack, and much more.
If youāre not already subscribed to the podcast, please take a second to subscribe on Apple Podcasts,Ā Google Podcasts, or Spotify.
On being in the Kali Yuga and when the woke get their hands on CRISPR
Razib Khan: I think weāre in the Kali Yuga. I think people are inverting normality. And I donāt think thatās sustainable. I think human nature is what it is. And it will ultimately come back to that into some sort of stable state.
Thereās only certain ways you can organize society.
Letās say polyamory. Okay. We have mutual friends who are into that sort of stuff.
This has been tried multiple times in United States history. It always peters out as a cultural phenomenon. Iām not saying that it goes extinct, but as a lifestyle choice and a cultural phenomenon, it always peters out, ācause guess what?
Most people canāt do this, and so this idea that everyone should experiment with their sexuality⦠No, you know, Iām Gen X. I can tell you, some people are born gay. Theyāre born that way. I think it was like an injustice that when they were young, they were demanded to make sure that they were, like it wasnāt natural for them.
Thatās not what they wanted to do. And so thatās why we, as a generation decided, they get to do their own thing. Let them be who they are.
Now, the pendulum has swung in a weird way where a lot of people are like you should experiment with your gender identity and your sexuality.
And Iām like, āYou should!ā
āBut donāt talk to me.ā
Justin Murphy: Just wait until those people get CRISPR.
Razib Khan: Yeah. Which is true. But thatās at least concrete, like if you wanna be a catman, CRISPR that up!
Justin Murphy: Yeah, [laughs] yeah.
Razib Khan: Like, more power to you. Thatās your choice. My only point is I think that people are trying to push a level of flexibility and openness on the typical American, typical human, where itās⦠No, weāre, most of us are pretty much template people.
Thereās a template, we age, we marry, we have children, itās like in the Indian system, youāre a young man, youāre a householder, and then you retire and you go into the forest to contemplate, stuff like that.
On antinatalism and welcoming our Amish overlords
Razib Khan: Antinatalism has a short shelf life. By definition, tautologically, it canāt become dominant and last for very long. Eventually the minority of people that want children will just inherit the earth ācause theyāre the only ones who have children. Now, you could have a situation where their children are converted every generation in some sort of equilibrium state. I think thatās what weāre seeing, religious people have had more children than nonreligious people for at least 200 years probably, but Americaās getting more and more secular because theyāre being converted.
You can have an equilibrium culturally but I do think that our current ageās fixation on individual self-actual- actualization, hedonism, and just living for the now, I think that has a short shelf life. Look at the doubling time of the Amish, thereās gonna be more than a million Amish, I think, by the end of the century.
Justin Murphy: So basically what youāre saying is that this is a non-issue because the atheist careerist types who donāt wanna have kids are just gonna exit the gene pool.
Razib Khan: Donāt hate on atheist careerists too much [laughs].
Justin Murphy: [laughs]
Razib Khan: I saw something in The New York Times or somewhere where it was basically like, ādonāt have children. I had children when I was young and it was a horrible decision. You should just go travel and experience the world.ā And to be judgmental I was just like, god, youāre such a hedonistic, pathetic human being. Iām just like, okay, Iāve traveled the world. Itās fine.
Justin Murphy: I was just gonna say, you can travel the world when youāre in your 20s and then also have a family [laughs].
Razib Khan: I just donāt get this whole idea. Itās āgotta smell the mountains on the other side of the world as well as the mountainsā¦ā Iām just saying: Children versus another building? I think buildings are great. I think architectureās great. I think nature is great, and different types of nature and architecture are great, but thereās something wrong in your value system when children are just not as exciting.
And Iām fine with people saying they donāt wanna have children. Just donāt have children. I donāt wanna hear about it anymore.
On the myths that ancient DNA will debunk and why gym bros are swarthy
Justin Murphy: What are the myths that you think people currently believe that will be disproven by ancient DNA?
Razib Khan: One thing that has been disproven by ancient DNA is continuity. So the idea was, humans spread out of Africa, they just settled, and everyoneās descended from the first people there.
It turns out thereās been multiple turnovers almost everywhere. So the first settlers often donāt last, they donāt stick. People get replaced. Thereās migration. Thereās replacement, thereās competition. So thatās definitely been a new revolution.
I think one myth in terms of people, what they think is, thereās been a lot of phenotypic evolution and we can infer it. We can look at the genome and make a statistical calculation. But itās different when you can concretely see it.
So I can tell you that I saw some RNH samples from Estonia. And something like 70 percent of the alleles of the genetic variants for eye color were for blue eyes. Today itās 95%. So thatās 2,500 years. There was no overall genome-wide change. There was no population moving in.
Justin Murphy: So what does that mean?
Razib Khan: That means there was natural selection.
Justin Murphy: Does that mean that humans prefer blue eyes, and soā¦
Razib Khan: People of northeast Europe have way more blue eyes than they did 2,000 years ago.
Justin Murphy: But Iām saying what do you think is the mechanism?
Razib Khan: We donāt know.
Justin Murphy: You think people are more likely to abort brown-eyed kids or something like that?
Razib Khan: I think people today are, but we donāt really know. People in the past, they had different preferences because they were on the Malthusian margin, right? I think itās not implausible that, because pigmentation pathways are hooked into a lot of⦠So if you take testosterone, youāre gonna get darker.
Justin Murphy: Like darker skin?
Razib Khan: Yeah. Because what happens with testosteroneā¦
It upregulates your melanocortin. So if you look at a lot of these gym bros, you start noticing theyāre a little like swarthy.
Justin Murphy: Fascinating. I always assumed that was tanning.
Razib Khan: But yeah, when men hit puberty, they get darker. After women hit menopause, they get darker ācause their testosterone to estrogen ratio shifts. So estrogen tends to make you paler. Testosterone makes you darker.
And thatās just a side effect of the fact that all these hormonal pathways are mixed in together.
Justin Murphy: Fascinating. Watchers of the show will know that if I start looking like a brown guy⦠Itās ācause Iām jacked up on testosterone. [laughs].
Razib Khan: I think they will maybe notice because of the thickness of the neck first, right?
If youāre not already subscribed to the podcast, please take a second to subscribe on Apple Podcasts,Ā Google Podcasts, or Spotify.